"Monocyte Migration and LFA-1-Mediated Attachment to Brain Microvascular Endothelia is Regulated by SDF-1alpha through Lyn Kinase"

Mona Malik, Ph.D. co-authored this article which discusses how infiltration of activated monocytes into the br ain is a prerequisite for the development of various neurological disorders such as HIV-associated dementia, multiple sclerosis, and other inflammatory processes. In these pathologies, the chemokine SDF-1 (CXCL12) is over-expressed and might attract monocytes into the CNS.

Mona Malik, Ph.D., supports patent prosecution and litigation and provides technical and scientific guidance in various fields of life sciences, including cell biology, immunology/immunotherapy, genetics, biochemistry, pharmacology, virology, oncology, plant sciences and agriculture. With an advance degree and more than a dozen years of research experience, Mona brings noteworthy credentials to the patent issues of intellectual property. She earned a Ph.D. from the University of Cambridge after investigating complex mechanisms of chromosomal gene recombination and gene replacement.

To read the full article, click the link below: